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Introduction

Travis W. Vandergriff Anatomy and Pathophysiology 1

Key features

ย„The relationship between structure and function of the skin is best demonstrated by presenting diseases that illustrate how skin can fail. Thus, disease reveals function, and function highlights structure

ย„The most obvious function of the skin is to maintain an internal environment that allows an organism to protect DNA and to reproduce it relatively faithfully

ย„Cutaneous structures include an epidermis that serves as a barrier

(preventing loss from within and damage from external insults) and a dermis that provides mechanical support, circulation, and nutrition. Other functions provided by the cells in the skin include immune recognition and memory, the ability to repair damage, thermoregulation, and communication

ย„Evidence that the skin has failed includes barrier disruption, infection, autoimmunity, cancer, and an appearance undesirable to the individual