๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
INTRODUCTION
Development of the human embryo is a complex process involving highly orchestrated cell movements, proliferation, death, and differentiation. This chapter focuses on key events and regulatory mechanisms that result in skin morphogenesis, maintenance, and regeneration. The spectrum of cutaneous abnormalities that can result from mutations in genes with critical roles in skin development is discussed. Ultimately, improved understanding of the pathways and signaling cascades essential to skin development will provide the basis for therapeutic approaches for patients with acquired as well as inherited skin disorders.