๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
EPIDEMIOLOGY
Mastocytosis can be present at birth or develop any time thereafter, including into late adulthood. Childhood-onset mastocytosis is defined as presenting prior to puberty. In a pediatric series (n=101), cutaneous mastocytosis appeared by ages 6 months and 2 years in 73% and 97% of children, respectively. Adult-onset mastocytosis most often develops in the third or fourth decade of life, has no sex preference, and occurs in all races.
While most individuals with mastocytosis have no family history of the disorder, there have been over 70 familial cases reported, including at least 15 sets of monozygotic twins; however, twin pairs discordant for the disease have also been described. Mastocytosis has been documented in three generations of a single kindred.