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Introduction
Christine J. Ko and Jennifer M. McNiff Cutaneous Metastases 122
Key features
ยCutaneous metastases are uncommon and rarely may be the presenting sign of an internal malignancy
ยIn general, cutaneous metastases are associated with a poor prognosis
ยIn women, breast carcinoma and melanoma are the malignancies that most frequently metastasize to the skin
ยIn men, melanoma and carcinomas of the head and neck, lung, and colon are the malignancies that most frequently metastasize to the skin
ยAmong common malignancies, breast carcinoma is the most likely to metastasize to the skin
ยThe most common clinical presentation for a cutaneous metastasis is a firm, painless, erythematous nodule
ยCutaneous metastases may arise in the anatomic vicinity of the primary cancer
ยCutaneous metastases typically have histologic features similar to, but not necessarily identical to, those of the primary malignancy
ยTreatments include excision, chemotherapy, immunotherapy, and radiotherapy; the latter is often administered for palliation