๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
HISTORY
A disease with thickened skin was first mentioned by Hippocrates (400 BCE). The term โsclerodermaโ is derived from the Greek words skleros (hard or indurated) and derma (skin). The first description of a generalized โhardnessโ of the skin in a young woman was by an Italian physician, Carlo Curzio, in 1753; the French physician Gintrac coined the term โsclรฉrodermieโ in 1847. Thomas Addison has been credited with the first detailed description of morphea in 1854, which he referred to as Alibertโs keloid syndrome. In 1924, Matsui described the typical histopathologic changes of scleroderma and in 1930 OโLeary and Nomland elaborated on the distinctive features of SSc versus morphea.