๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
EPIDEMIOLOGY
Even though morphea has been long recognized as a well-defined entity, few population-based studies exist. A survey from Olmsted County, Minnesota attempted to register all patients with the disorder from 1960 to 1993. During this period, the annual incidence rate was 27 per million. According to this study, 56% of patients had plaque-type, 20% linear, 13% generalized, and 11% deep morphea. The prevalence of morphea increases with age, occurring in ~500 and 2200 per million at ages 18 and 80 years, respectively. The disease is more prevalent in women than in men (2.6โ:โ1), with the exception of linear morphea, which has no sex preference. Data published on the incidence and prevalence of morphea probably reflect an underestimation, as they critically depend on clinical recognition and diagnosis.
Morphea is rarely life-threatening. In the Olmsted County study, the survival rate of patients with morphea was not significantly different from that of the general population. However, in 11% of the patients, substantial disability occurred. This is of particular concern since disability occurs primarily with linear morphea, which has its onset before age 18 years in two-thirds of patients.