Introduction
Key features
The cutaneous mucinoses are a heterogeneous group of disorders in which an abnormal amount of mucin accumulates in the skin
The etiopathogenesis of cutaneous mucinoses is unknown
The cutaneous mucinoses are divided into two groups: (1) primary cutaneous mucinoses, in which the mucin deposition leads to clinically distinctive lesions and is the major histologic feature; and (2) secondary mucinoses, in which the mucin deposition is simply an associated finding
Primary cutaneous mucinoses are further divided into degen- erative–inflammatory forms (which may be dermal or follicular) and hamartomatous–neoplastic forms
Associated disorders include paraproteinemia (scleromyxedema, scleredema), diabetes mellitus (scleredema), thyroid disease (pretibial myxedema, myxedema), and autoimmune connective tissue disease (lupus erythematosus, dermatomyositis)