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Introduction

Rachel Reynolds, Kristen Corey and Francisco M. Camacho Hypertrichosis and Hirsutism

Key features

ย„Hypertrichosis refers to excessive growth of hair anywhere on the body, whereas hirsutism represents excessive hair growth within androgen-dependent sites in girls and women

ย„Hypertrichosis may be generalized or localized, with etiologies ranging from genodermatoses to underlying hamartomas to repeated trauma

ย„Hirsutism is related to hormonal factors, in particular an increase in circulating androgen levels and/or enhanced sensitivity of hair follicles to androgens

ย„In women, the major sources of androgens are the adrenal glands and the ovaries; dysfunction of these organs must be considered when a patient presents with hirsutism

ย„Depending on its etiology, treatment of hirsutism may include oral contraceptives, antiandrogens, gonadotropin-releasing hormone agonists, glucocorticoids, and insulin-lowering agents, combined with topical medications and physical measures (e.g. laser hair removal)