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EPIDEMIOLOGY
In 2020, the United Nations Office on Drugs and Crime estimated that globally 36 million people suffered from drug use disorders, but only a minority had received necessary treatment. According to theย 2019 National Survey on Drug Use and Health (NSDUH), 20.4 million Americans age 12 years or older experienced a substance use disorder during that year (Fig. 89.1). The statistics were as follows: 71% had an alcohol use disorder, 41% had an illicit drug use disorder, and 12% had both. Drug abuse and addiction has cost American society more than $740 billion annually in lost workplace productivity, healthcare expenses, and crime-related costs.

Fig. 89.1 2019 National Survey on Drug Use and Health โ drug use in Americans 12 years of age or older during the past year. An estimated 10.8 million individuals experienced illicit drug use disorder +/- alcohol use disorder. Hallucinogens include MDMA (ecstasy), lysergic acid (LSD), and phencyclidine (PCP). From Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: Results from the 2019 National Survey on Drug Use and Health (HHS Publication No. PEP20-07-01-001, NSDUH Series H-55). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration 2020. Available at: https:// www.samhsa.gov/data/.