๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Introduction
Julie V. Schaffer* Mosaicism and Linear Lesions 62
Key features
ยMosaicism for genes expressed in the skin presents as a patchy distribution of affected and unaffected skin
ยThe classical pattern follows the lines of Blaschko but varies according to cell type and timing of mosaicism
ยEpidermal nevi represent mosaicism for a variety of genes with variable associated features
ยSome mosaic disorders are recognizable as segmental forms of autosomal dominant skin disorders
ยIf there is also gonadal mosaicism, offspring may have the
ยญcorresponding generalized condition