๐Ÿ—‚ ็ธฝ็›ฎ้Œ„ ๏ฝœ ๐Ÿ“– ่‹ฑๆ–‡ๅŽŸๆ–‡๏ผˆๆœฌ็ฏ‡๏ผ‰ ๏ฝœ ๐Ÿ“ ๅฎŒๆ•ด็ฟป่ญฏ ๏ฝœ โญ ็ฒพ่ฏ็ญ†่จ˜

Lipedematous Scalp and Lipedematous Alopecia

Lipedematous scalp is a disease of unknown etiology that is associated with local lymphatic dilatation and edematous thickening of the subcutis and dermis. Patients have a soft, โ€œspongyโ€ scalp and when pressed with a finger, a depression is seen. If associated with hair loss, then it is referred to as lipedematous alopecia. Hairs are usually sparse and short (~1โ€“2โ€‰cm). By trichoscopy, multiple thin and vellus hairs as well as linear areas of erythema with fine arborizing vessels are seen.

The primary pathologic finding is an approximate doubling of scalp thickness as a result of expansion of the subcutaneous fat layer. If there is prominent alopecia, histopathologic changes include not only a thickened adipose layer, but also replacement of hair follicles with fibrous tracts without discernible inflammation. In case reports, partial hair regrowth has been described with topical clobetasol, intralesional triamcinolone, or mycophenolate mofetil.