大疱性藥物疹（BULLOUS DRUG ERUPTIONS）
重點特徵（Key features）
某些藥物疹可以水疱性疹的形式表現
這些疹子可為局部性或廣泛性
臨床、組織學與免疫螢光表現各異，取決於藥物疹的型態
小水疱與大疱可在多種藥物疹中發生，這些藥物疹概述於表 33.1，並於其他章節中詳細討論。
表 33-1：大疱性藥物疹。偶爾，濕疹樣藥物反應（例如次發於 warfarin、鈣離子通道阻斷劑、angiotensin converting enzyme［ACE］抑制劑、angiotensin II 受體阻斷劑）與全身性接觸性皮膚炎可呈丘疹水疱性；罹患 drug reaction with eosinophilia and systemic symptoms（DRESS）／drug-induced hypersensitivity syndrome（DIHS）以及藥物誘發 Sweet syndrome 的病人亦可能出現小水疱。昏迷性水疱與大疱性小血管炎於內文中討論。
Table 33.1 Bullous drug eruptions. Occasionally, eczematous drug reactions (e.g. secondary to warfarin, calcium channel blockers, angiotensin converting enzyme [ACE] inhibitors, angiotensin II receptor blockers) and systemic contact dermatitis can be papulovesicular; patients with drug reaction with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS) and drug-induced Sweet syndrome can also develop vesicles. Coma blisters and bullous small vessel vasculitis are discussed in the text. EGFR, epidermal growth factor receptor; NSAIDs, nonsteroidal anti-inflammatory drugs.